In a Milestone for A.L.S., a Treatment Helps Some Patients Improve
From the New York Times, May 6, 2026 The development of tofersen stemmed largely from the early fundamental research by…
Breaking Research
New Study Links ITCH Protein to a Common Trigger in Alzheimer’s and ALS
Packard-funded investigator Jiou Wang, MD, PhD, of Johns Hopkins University, has helped uncover a surprising culprit behind a…
Johns Hopkins Medicine and Packard Center Investigator-Led Team Develops Fluid Biomarker for Early Detection of Degenerative Diseases ALS And FTD
Funding for this study was provided by the Packard Center. Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS,…
FDA grants accelerated approval of tofersen for treatment of SOD1-ALS
The Food and Drug Administration granted accelerated approval of the drug tofersen for the treatment of SOD1-ALS. Developed by…
Research Byte: Packard researchers identify new function of C9 protein
In a new paper in PLOS Genetics, Packard researcher Jiou Wang identified a new mechanism through which C9orf72…
Answer ALS Launches ‘The Data is Here’ Campaign to Announce the Release of the World’s Largest Open-Sourced ALS Data Portal
Answer ALS Launches ‘The Data is Here’ Campaign to Announce the Release of the World’ Largest Open-Sourced ALS…
ALS Pathology Linked to Defects in the Cell Nucleus
Packard researchers used Answer ALS cell lines to show that the protein CHMP7 accumulates in the nucleus, triggering…
The Pathway to Discovery and Hope for ALS Patients and Researchers: A massive biological genetic and clinical resource for ALS and neurodegenerative diseases.
Every year, 5,000 Americans are diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, that…