Baharah Ajami, PhD
Oregon Health & Science University
Microglia regulation of selective neuronal vulnerability associated with amyotrophic lateral sclerosis (ALS)
In ALS, ocular motor neurons are more resistant to degeneration than other upper and lower motor neurons. Microglia, the immune cells of the brain can elicit both neuroprotective and neurotoxic effects and thus influence neuronal degeneration. In this project, we will study the role of microglia in motor neuron vulnerability using several cutting edge technologies.